Scientific Publications
Anders Asbjørn Jensen and Emil Märcher-Rørsted in the laboratories in Copenhagen (October 2020). Lophora’s founders have a proven track record of academic excellence demonstrated by numerous influential scientific publications within the field of psychedelic research published in peer reviewed journals over the past 15 years.
Representative scientific publications from the Lophora-research team:
- Animal Behavior in Psychedelic Research. Odland, A.U.; Kristensen, J.L.; Andreasen, J.T. Pharm. Rev. 2022, 74, 1176.
- 25CN‐NBOH: A Selective Agonist for in vitro and in vivo Investigations of the Serotonin 2A Receptor. Marcher-Rørsted, E.; Jensen, A.A.; Kristensen, J.L. ChemMedChem 2021, 16, 3263.
- Investigation of the 2,5-dimethoxy motif in phenethylamine Serotonin 2A receptor agonists. Marcher-Rørsted, E.; Halberstadt, A.L.; Klein, A.; Chatha, M.; Jademyr, S.; Jensen, A.A.; Kristensen, J.L. ACS Chem. Neurosci. 2020, 11, 1238.
- Dark classics in chemical neuroscience: NBOMes. Poulie, C.B.M.; Jensen, A.A.; Halberstadt, A.L.; Kristensen, J.L. ACS Chem. Neurosci. 2020, 23, 3860.
- Human biodistribution and radiation dosimetry of the 5-HT2A receptor agonist Cimbi-36 labeled with carbon-11 in two positions. Johansen, A.; Holm, S.; Dall, B.; Keller, S.; Kristensen, J.L.; Knudsen, G.M.; Hansen, H.D. EJNMMI Research 2019, 9, 71.
- Detailed characterization of the in vitro pharmacological and pharmacokinetic properties of N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine (25CN-NBOH), a highly selective and brain-penetrant 5-HT2A receptor agonist. Jensen, A.A.; McCorvy, J.D.; Leth-Petersen, S.; Bundgaard, C.; Liebscher, G.; Kenakin, T.P.; Brauner-Osborne, H.; Kehler, J.; Kristensen, J.L. JPET 2017, 361, 441-453.
- 5-HT2A/5-HT2C Receptor Pharmacology and Intrinsic Clearance of N-Benzylphenethylamines Modified at the Primary Site of Metabolism. Leth-Petersen, S.; Petersen, I.N.; Jensen, A.A.; Bundgaard, C.; Bæk, M.; Kehler, J.; Kristensen, J.L. ACS Chem. Neurosci. 2016, 7, 1614-1619.
- Metabolic fate of hallucinogenic NBOMes. Leth-Petersen, S.; Gabel-Jensen, C.; Gillings, Nic.; Lehel, S.; Hansen, H.D.; Knudsen, G.M.; Kristensen, J.L. Chem Res. Toxicol. 2016, 29, 96-100.
- Hallucinogen-like effects of 2-([2-(4-cyano-2,5-dimethoxyphenyl) ethylamino]methyl)phenol (25CN-NBOH), a novel N-benzylphenethylamine with 100-fold selectivity for 5-HT2A receptors, in mice. Fantegrossi, W.; Gray, B.; Bailey, J.; Smith, D.; Hansen, M.; Kristensen, J. Psycopharmacology, 2015 232(6), 1039-47.
- Serotonin 2A receptor agonist binding in the human brain with [11C]Cimbi-36. Ettrup, S. Cunha-Bang, B. McMahon, S. Lehel, A. Dyssegaard, A.W. Skibsted, L.M. Jørgensen, M. Hansen, A.O. Baandrup, S. Bache, C. Svarer, J.L. Kristensen, N. Gillings, J. Madsen, G.M. Knudsen. JCBFM, 2014, 34, 1188.
- Synthesis and Structure-Activity Relationships of N-Benzyl Phenethylamines as 5-HT2A/2C Agonists. M. Hansen, K. Phonekeo, J.S. Paine, S. Leth-Petersen, M. Begtrup, H. Bräuner-Osborne, J.L. Kristensen. ACS Chem. Neurosci. 2014, 5, 243.
- Structure-Activity Relationships of Constrained Phenylethylamine Ligands for the Serotonin 5-HT2 Receptors. V. Isberg, J. Paine, S. Leth-Petersen, J.L. Kristensen, D.E. Gloriam. PLoS ONE, 2013, 8(11): e78515.
- Radiosynthesis and in vivo evaluation of a series of substituted 11C-phenethylamines as 5-HT2A agonist PET tracers. Ettrup, A.; Hansen, M.; Santini, M.A.; Paine, J.; Gillings, N. Palner, M.; Lehel, S.; Herth, M.M.; Madsen, J.; Kristensen, J.; Begtrup, M.; Knudsen, G.M. Eur. J. Nucl. Med. Mol. Imaging, 2011, 38, 681.