Lophora Initiates Preclinical Development of LPH-5 for Treatment-Resistant Depression

Lophora has been granted a $1.5M convertible loan by the Novo Nordisk Foundation to advance their first-in-class lead candidate LPH-5.
In early 2020, Lophora was successfully accepted into the Creation House program at BioInnovation Institute and granted a $1.5M convertible loan by the Novo Nordisk Foundation.
Lophora will now advance their lead candidate LPH-5 through pre-clinical development in order to de-risk the compound prior to the initiation of first-in-human studies towards the end of 2021. Amongst other things, this involves the large-scale production of LPH-5, followed by a detailed characterization of the molecule’s safety profile, which is a key regulatory requirement prior to initiating clinical studies.